Human endometrium: immunohistochemical staining for Muc-1. Note luminal cytoplasmic staining of superficial epithelial cells and glandular epithelium. Muc-1 Glycoprotein: clone Ma695

Muc Glycoprotein Antibodies

muc-glycoprotein-antibodies

Antigen Background

Mucins are heavily glycosylated glycoproteins which constitute the major components of mucus that covers the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have shown that these mucins are differentially expressed in epithelia with cell-type specificity. The normal gastric mucosa shows cell-type specific expression of Muc-1, Muc-5AC and Muc-6 glycoproteins with the first two mucins found in superficial epithelium and Muc-6 glycoprotein in the deep glands. Muc-1 and Muc-5AC glycoproteins are expressed in many epithelia but Muc-6 glycoprotein is mainly expressed in gastric mucosa. In addition, Muc-2 glycoprotein is not expressed in normal gastric mucosa.

Product Notification

PA0051, PA0052 and PA0053 are for use with BDD v 75 for BOND Software version 5.1 and higher. Please contact your local Leica Biosystems Representative with any questions.

Disclaimer
Muc Glycoprotein Antibodies is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Products

Products

PA0155
7mL Muc-2 (CCP58) Bond RTU Primary
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This item replaces MUC-2MUC-2-CE
CCP58
Gastrointestinal Pathology
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml
PA0052
7mL Muc-5AC Glycoprotein (CLH2) Bond RTU
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CLH2
Gastrointestinal Pathology
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml
PA0053
7mL Muc-6 Glycoprotein (CLH5) Bond RTU
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CLH5
Gastrointestinal Pathology
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml
PA0051
7ml Muc-1 Glycoprotein (Ma695) Bond RTU
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Ma695
Gastrointestinal Pathology
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Downloads

Downloads

PA0155

PA0052

PA0053

PA0051

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