Colonic adenocarcinoma: immunohistochemical staining for Sialyl Lewis antigen. Note the enhancement of the luminal membrane staining of colonic epithelial cells. CA19-9: clone C241:5:1:4

CA19-9 (Sialyl Lewis a)

ca19-9-sialyl-lewis-a

Antigen Background

CA19-9 is an epitope on the sialylated Lewisa carbohydrate structure. Sialylated Lewisa plays a role in cell adhesion by acting as a functional ligand for the inducible adhesion molecule E-selectin. CA19-9 and CA50 (carcinoma associated mucin antigen) are useful serum markers in the diagnosis and follow up of gastrointestinal and pancreatic cancers. In carcinoma of the pancreas, it is reported that the immunohistochemical expression of both CA19-9 and CA50 correlates with tumor differentiation, where the strongest staining is observed in well-differentiated tumors. These two markers are also reported in a number of benign lesions such as chronic pancreatitis.

Product Specific Information

Clone C241:5:1:4 reacts specifically with Sialyl Lewisa - containing glycolipids, showing no crossreaction with Lewisa, Lewisb, or other structurally related molecules. The epitope recognized by NCL-L-CA19-9 is designated CA19-9.

Disclaimer

CA19-9 (Sialyl Lewisa) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains. 

To view pricing, add to cart and log in.
Contact Us for a quote.
background-img
$99 BOND RTU's
It's easy, get your RTU's at our online shop today!

Products

Products

CA19-9-L
1ml NCL-L-CA19-9
Log in for Availability
Ships via Overnight
To view pricing, add to cart and log in.
Contact Us for a quote.
PA0424
7ml CA19-9 Bond RTU Primary
Log in for Availability
Ships via Overnight
To view pricing, add to cart and log in.
Contact Us for a quote.

Downloads

Downloads

CA19-9-L

PA0424

Recently Viewed