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Informações do antígeno
O complexo CD79 é um heterodímero ligado por dissulfureto que é associado não-covalentemente com imunoglobulinas ligadas à membrana nas células B. Este complexo de polipéptidos e imunoglobulina constituem o receptor de antígeno de células B. Os dois componentes deste complexo são designados CD79a e CD79b. O antígeno CD79a foi relatado como aparecendo primeiro na pré fase de células B, no início da maturação, e persistir até o estágio celular plasmático onde se encontra como um componente intracelular. O antígeno CD79a foi relatado como expresso na maioria das leucemias agudas de precursor tipo celular B, linhas de células B, linfomas celulares B e em alguns mielomas. Não está presente em mieloide ou linhas de células T.
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