6q21

6q21

6q21 / SE 6

Deletions affecting the long arm of chromosome 6 (6q) are among the most commonly observed chromosomal aberrations in lymphoid malignancies and have been identified as adverse prognostic factor in subsets of tumors including CLL. A minimal deletion region has been identified within a 2-megabase segment of 6q21, between D6S447 and D6S246. The SEC63 gene is located within this critical region. 

6q21 / MYC (8q24)

Deletions affecting the long arm of chromosome 6 (6q) involving band 6q21 are among the most commonly observed chromosomal aberrations in lymphoid malignancies and have been identified as adverse prognostic factor in subsets of tumors. Amplification of MYC (MYC, 8q24) has been described in many types of solid tumors, such as breast, cervical and colon cancers, as well as in myeloma, non‐Hodgkin's lymphoma, gastric adenocarcinomas and ovarian cancer.

References:

Stilgenbauer S et al, 1999, Leukemia, 13; 1331‐1334
Sherratt et al. 1997, Chromosome Res, 5: 118-124.
Zhang et al. 2000, Genes Chrom Cancer, 27: 52-58.
Bentz, M et al, 1995, Blood, 85; 3610‐3618

  • KBI-10117
    6q21 / MYC (8q24)
  • KBI-10105
    6q21 / SE 6
  • KI-10117
    6q21 / MYC (8q24)
  • KI-10105
    6q21 / SE 6

Produktspezifikationen

Produktspezifikationen

KBI-10117
Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Deletion Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KBI-10105
Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Deletion
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KI-10117
Research
Research Use Only
11 test
Dual Color > Red, Green
Cells
Deletion Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KI-10105
Research
Research Use Only
10 test
Dual Color > Red, Green
Cells
Deletion
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent

Dokumente

Dokumente

Ressourcen

Ressourcen

6q21 / SE 6

Deletions affecting the long arm of chromosome 6 (6q) are among the most commonly observed chromosomal aberrations in lymphoid malignancies and have been identified as adverse prognostic factor in subsets of tumors including CLL. A minimal deletion region has been identified within a 2-megabase segment of 6q21, between D6S447 and D6S246. The SEC63 gene is located within this critical region. 

6q21 / MYC (8q24)

Deletions affecting the long arm of chromosome 6 (6q) involving band 6q21 are among the most commonly observed chromosomal aberrations in lymphoid malignancies and have been identified as adverse prognostic factor in subsets of tumors. Amplification of MYC (MYC, 8q24) has been described in many types of solid tumors, such as breast, cervical and colon cancers, as well as in myeloma, non‐Hodgkin's lymphoma, gastric adenocarcinomas and ovarian cancer.

References:

Stilgenbauer S et al, 1999, Leukemia, 13; 1331‐1334
Sherratt et al. 1997, Chromosome Res, 5: 118-124.
Zhang et al. 2000, Genes Chrom Cancer, 27: 52-58.
Bentz, M et al, 1995, Blood, 85; 3610‐3618

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