Human skin, melanoma: immunohistochemical staining for Melan A. Note the melanoma showing cytoplasmic staining of tumor cells. Melan A: clone A103

Melan A

melan-a

Antigen Background

Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.

Disclaimer

Melan A is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • This item replaces MELANA-R-7-CEMELANA-L-CE-SMELANA-OMELANA-CE-SMELANA-L-SMELANA-CE
    MELANA-L-CE
    1ml NCL-L-MelanA
    A103
    Liquid Concentrate
    P (HIER)
  • PA0044
    30ml Melan A Bond RTU Primary
    A103
    BOND RTU
    P (HIER)
  • PA0233
    7ml Melan A Bond RTU Primary
    A103
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

MELANA-L-CE
Dermatopathology
A103
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0044
Dermatopathology
A103
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
30ml
PA0233
Dermatopathology
A103
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

MELANA-L-CE
PA0044
PA0233

Resources

Resources

Antigen Background

Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.

Disclaimer

Melan A is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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