Human skin, melanoma: immunohistochemical staining for Melan A. Note the melanoma showing cytoplasmic staining of tumor cells. Melan A: clone A103

Melan A

melan-a

Antigen Background

Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.

Disclaimer

Melan A is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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MELANA-L-CE
1ml NCL-L-MelanA
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PA0044
30ml Melan A Bond RTU Primary
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PA0233
7ml Melan A Bond RTU Primary
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MELANA-L-CE

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