Human thymoma: immunohistochemical staining for CD1a. Note the neoplastic cells show a moderate to strong and distinct membrane staining reaction. CD1a: clone MTB1

CD1a

cd1a

Antigen Background

CD1a is a protein of 43 to 49 kD expressed on dendritic cells and cortical thymocytes. CD1a antigen expression has been shown to be useful in differentiating Langerhans cells, powerful antigen presenting cells present in skin and epithelia, from interdigitating cells. Immunohistochemical studies for CD1a antigen have reported a reduction in epidermal Langerhans cells in graft versus host disease and the participation of CD1a antigen-positive dendritic cells in atherosclerotic lesion formation and asthmatic inflammation.

Product Specific Information

Clone MTB1 detects cortical thymocytes, Langerhans cells in epidermis, interdigitating cells of dermis and interdigitating cells of stratified squamous epithelium of tonsil. Clone MTB1 may also detect small focal groups of lymphocytes outside the germinal centers of tonsil indicating a cross-reaction with CD1b antigen.

Disclaimer

CD1a is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Products

Products

CD1A-235-L-CE-H
0.5ml NCL-L-CD1a-235
Login for Stock

Ships via Overnight
To view pricing, add to cart and log in.
Contact Us for a quote.

MTB1
Dermatopathology
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD1A-235-L-CE
1ml NCL-L-CD1a-235
Login for Stock

Ships via Overnight
To view pricing, add to cart and log in.
Contact Us for a quote.

This item replaces CD1A-235-CE-SCD1A-235-CECD1A-235-L-SCD1A-235-L-CE-SCD1A-220CD1A-235-R-7-CECD1A-220-OCD1A-235-R-7CD1A-220-SCD1A-235-SCD1A-235-L
MTB1
Dermatopathology
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0235
7ml CD1a Bond RTU Primary
Login for Stock

Ships via Overnight
To view pricing, add to cart and log in.
Contact Us for a quote.

MTB1
Dermatopathology
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Downloads

Downloads

CD1A-235-L-CE-H

CD1A-235-L-CE

PA0235

Recently Viewed