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Informações do antígeno
O conteúdo do receptor de estrógeno (ER) de tecido cancerígeno mamário é um parâmetro importante na predição de prognóstico e resposta a terapia endócrina. A introdução de anticorpos monoclonais altamente específicos a ER tem permitido a determinação do estado do receptor de tumores de mama serem executados em laboratórios de rotina histopatológica.
O clone 6F11 é aumentado até a forma de comprimento total alfa da molécula de receptor de estrogênio presente no antígeno ER humano, localizado no núcleo das células normais e neoplásicas positivas ER. O clone 6F11 tem sido extensivamente testado.
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