BOND Kappa Probe
There are five classes of immunoglobulin, determined by the type of heavy chain. In contrast, there are only two types of light chain: Kappa or Lambda. Each individual immunogloblin molecule is composed of one of five classes of heavy chains and either Kappa or Lambda light chains. In normal human lymphoid populations, the ratio of Kappa to Lambda light chains is approximately 2:1.
Kappa Probe is used in conjunction with Lambda Probe for the detection of antibody producing B-cells in formalin-fixed, paraffin embedded tissue.