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Antigen Background
CD79b は、CD79a とヘテロ二量体の複合体として存在し、細胞表面免疫グロブリン(sIg)と会合してB 細胞抗原レセプター(BCR)を形成する分子で、免疫グロブリン・スーパーファリミーに属します。CD79b は別名B29、Ig-βとしても知られています。BCR の発現はB 細胞系に限定され、プレB 細胞期の直後に細胞表面に発現し、形質細胞期に入る前に消失します。腫瘍では80-90% のB 細胞性腫瘍で発現していますが、慢性B 細胞性リンパ性白血病では発現していません。
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