Antigen Background
The expression of different cytokeratins in epithelial-derived tumors and the general tendency towards maintenance of cytokeratin polypeptide patterns during malignant growth and metastasis serves as a basis for approaching the characterization of tumors, using cytokeratins as differentiation markers.
Origin Cytokeratin (Clone 34?E12) is recommended for the characterization of squamous and ductal carcinomas arising from complex epithelia and is of value in the differentiation of benign and malignant small acinar lesions of the prostate gland.