19q13 / TP53 (17p13) hybridized to patient material showing a TP53 (17p13) deletion (1R2G).

IVD 19q13/TP53

ivd-19q13-tp53
TP53 (previously known as p53) gene deletion, which can be identified by interphase FISH in almost a third of patients with newly diagnosed MM, is a prognostic factor predicting for short survival of MM patients treated with conventional-dose chemotherapy. Amplification of 19q13 has been reported in a variety of cancer. The 19q13 specific FISH probe is optimized to detect copy numbers at 19q13. The TP53 (17p13) specific DNA region is optimized to detect copy numbers of the TP53 gene region at 17p13.

References:
Drach et al, 1998, Blood, 92; 802-809.
Cremer et al, 2005, Genes Chrom Cancer, 44; 194-203.
  • KBI-10509
    Checar Disponibilidade
    ON MM 19q13 / p53 (17p13)

Especificaç÷es de Produtos

Especificaç÷es de Produtos

KBI-10509
Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Deletion Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent

Documentos

Documentos

Recursos

Recursos

TP53 (previously known as p53) gene deletion, which can be identified by interphase FISH in almost a third of patients with newly diagnosed MM, is a prognostic factor predicting for short survival of MM patients treated with conventional-dose chemotherapy. Amplification of 19q13 has been reported in a variety of cancer. The 19q13 specific FISH probe is optimized to detect copy numbers at 19q13. The TP53 (17p13) specific DNA region is optimized to detect copy numbers of the TP53 gene region at 17p13.

References:
Drach et al, 1998, Blood, 92; 802-809.
Cremer et al, 2005, Genes Chrom Cancer, 44; 194-203.

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