IGH (14q32) Break probe hybridized to patient material showing a partial deletion of 14q32 (1RG1R).

IVD IGH Break

ivd-igh-break
Multiple myeloma is characterized by complex rearrangements involving the IgH gene, particularly at the constant locus. The IgH rearrangement provides a useful marker of clonality in B-cell malignancies and amplification of this rearrangement is the method of choice to monitor the residual tumor cells in multiple myeloma. The IGH (14q32) break probe is optimized to detect translocations involving the IGH gene region at 14q32 in a dual-color, split assay.

References:
Taniwaki et al, 1994, Blood, 83; 2962-1969.
Gozetti et al, 2002, Cancer Research, 62; 5523-5527.

Products

Products

KBI-10601
ON IGH (14q32) Break
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Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Translocation
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent

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