BCR / ABL1 t(9;22), Dual-Color, Single-Fusion probe hybridized to patient material showing t(9;22) translocation (1RG1R1G). Material kindly provided by Dr. Balogh, Budapest.

IVD BCR/ABL1 DC ES

ivd-bcr-abl1-dc-es
A simple dual-color, single-fusion assay is preferably used for the initial screening of CML and ALL patients. The Philadelphia chromosome, der(22q), is visualized by a fusion signal while the der(9q) shows no signal. The BCR/ABL1 t(9;22) FISH probe is optimized to detect the t(9;22)(q34;q11) reciprocal translocation in a dual-color, single-fusion, extra-signal assay on metaphase/interphase spreads, blood smears and bone marrow cells.

References:
Morris et al, 1990, Blood, 76; 1812-1818.
Dewald et al, 1998, Blood, 91; 3357-3365.
Kolomietz et al, 2001, Blood, 97; 3581-3588.
Huntly et al, 2003, Blood, 102; 1160-1168.
Tkachuk et al., 1990, Science, 250; 559-562.

Products

Products

KBI-10008
ON BCR/ABL t(9;22) DC S-Fusion ES
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Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Translocation
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent

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