Human tonsil: immunohistochemical staining for von Willebrand Factor. Note cytoplasmic staining of endothelial cells. Von Willebrand Factor: clone 36B11

von Willebrand Factor (Factor VIII-related antigen)

human-von-willebrand-factor

Antigen Background

Human von Willebrand factor (or factor VIII-related antigen) is a 270 kD multimeric plasma glycoprotein. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein Ib/IIIa, collagen and heparin. Von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular origin.

Disclaimer

von Willebrand Factor (Factor VIII-related antigen) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Produkte

Produkte

VWF-L
1ml NCL-L-vWF
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VWF-L-CE
1ml NCL-L-vWF
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PA0400
7ml VWF Bond RTU Primary
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PA0055
7ml vWF (36B11) Bond RTU Primary
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Downloads

Downloads

VWF-L

VWF-L-CE

PA0400

PA0055

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