Thyroid, Graves' disease: immunohistochemical staining for Thyroid Peroxidase. Note intense cytoplasmic staining of thyroid epithelial cells. Thyroid Peroxidase: clone AC25

Thyroid Peroxidase

thyroid-peroxidase

Antigen Background

Thyroid peroxidase gene expression is under the regulation of thyroid stimulating hormone. In normal thyroid, expression of thyroid peroxidase (TPO) described immunohistochemically is reported to produce a diffuse, fine, granular cytoplasmic stain in all follicular cells. Some studies have shown qualitative, as well as quantitative differences in thyroid peroxidase expression in thyroid cancer compared to normal tissue.


Product Specific Information

TPO stains optimally when used in TBS-based wash buffer and diluent systems.


Disclaimer

Thyroid Peroxidase is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • This item replaces TPO-L-CE-S
    TPO-L-CE
    1ml NCL-L-TPO
    AC25
    Liquid Concentrate
    P (HIER)

Product Specifications

Product Specifications

TPO-L-CE
Head, Neck and Endocrine
AC25
Liquid Concentrate
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml

Documents

Documents

TPO-L-CE

Resources

Resources

Antigen Background

Thyroid peroxidase gene expression is under the regulation of thyroid stimulating hormone. In normal thyroid, expression of thyroid peroxidase (TPO) described immunohistochemically is reported to produce a diffuse, fine, granular cytoplasmic stain in all follicular cells. Some studies have shown qualitative, as well as quantitative differences in thyroid peroxidase expression in thyroid cancer compared to normal tissue.


Product Specific Information

TPO stains optimally when used in TBS-based wash buffer and diluent systems.


Disclaimer

Thyroid Peroxidase is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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