Human prostatic hyperplasia: immunohistochemical staining of Prostate Specific Antigen. Note the cytoplasmic and membrane staining of hyperplastic glandular epithelial cells. Prostate Specific Antigen: clone 35H9 

Prostate Specific Antigen

prostate-specific-antigen

Antigen Background

Prostate specific antigen (PSA) is a 34 kD protein belonging to the kallikrein family of serine proteases and was originally isolated and purified from human seminal plasma. It was found to be immunologically identical and biologically similar to a protein isolated from the prostate gland. PSA is distinct from prostatic acid phosphatase. Low levels of expression of PSA have been reported in non-prostatic tissues and tumors such as breast carcinomas.

Prostate Specific Antigen is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • PSA-431-L-CE
    1ml NCL-L-PSA-431
    35H9
    Liquid Concentrate
    P
  • PA0431
    7ml PSA Bond RTU Primary
    35H9
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

PSA-431-L-CE
Uropathology
35H9
Liquid Concentrate
Yes
P
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0431
Uropathology
35H9
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

PSA-431-L-CE
PA0431

Resources

Resources

Antigen Background

Prostate specific antigen (PSA) is a 34 kD protein belonging to the kallikrein family of serine proteases and was originally isolated and purified from human seminal plasma. It was found to be immunologically identical and biologically similar to a protein isolated from the prostate gland. PSA is distinct from prostatic acid phosphatase. Low levels of expression of PSA have been reported in non-prostatic tissues and tumors such as breast carcinomas.

Prostate Specific Antigen is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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