Immunohistochemical staining for mismatch repair protein (PMS2). Note nuclear staining in a high proportion of the malignant cells. Mismatch Repair Protein (PMS2): clone EP51.

Mismatch Repair Protein (PMS2)

mismatch-repair-protein-pms2

Antigen Background

Mismatch repair gene Postmeiotic segregation Increased 2, also known as PMS1 homolog 2, is a ubiquitous gene encoding the mismatch repair protein (MMR) PMS1 protein homolog 2 (PMS2). PMS2 functions by repairing mutations occurring during DNA replication, in normal proliferating cells.

Disclaimer

Mismatch Repair Protein (PMS2) is recommended for the detection of specific antigens of interest in normal and neoplastic tissue, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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1ml NCL-L-PMS2
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7ml PMS2 (EP51) Bond RTU Primary
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PMS2-L-CE

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