Immunohistochemical staining for mismatch repair protein (MSH2). Note nuclear staining in a high proportion of the malignant cells. Mismatch Repair Protein (MSH2): clone 79H11.

Mismatch Repair Protein (MSH2)

mismatch-repair-protein-msh2

Antigen Background

Mismatch repair gene MutS Homolog 2 is a ubiquitous gene encoding the mismatch repair protein (MMR) MutS protein homolog 2 (MSH2). MSH2 functions by repairing mutations occurring during DNA replication, in normal proliferating cells.

Disclaimer

Mismatch Repair Protein (MSH2) is recommended for the detection of specific antigens of interest in normal and neoplastic tissue, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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PA0989
7ml MSH2 (79H11) Bond RTU Primary
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