Human ductal carcinoma of breast: immunohistochemical staining for Mammaglobin protein. Note cytoplasmic staining of a proportion of malignant cells. Mammaglobin: clone EP249

Mammaglobin

mammaglobin

Antigen Background

Mammaglobin is a 93 kDa glycoprotein that belongs to the uteroglobin family of proteins. It was first described in 1996 and found to be overexpressed in breast cancer. Published reports suggest a role for mammaglobin in the diagnosis of metastatic breast carcinoma.
Mammaglobin has been suggested as a useful marker for carcinomas of unknown primary origin, with expression unaltered from the primary site. Additional published data suggests a role for mammaglobin in the migration and invasion of breast cancer cells.

Disclaimer

Mammaglobin is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • PA0802
    7ML Mammaglobin (31A5 Rab) 'CM'
    PREDIL
  • PA0378
    7ml Mammaglobin (EP249) Bond RTU Primary
    EP249
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

PA0802
PREDIL
Rabbit
7ml
PA0378
Breast Pathology
EP249
BOND RTU
No
P (HIER)
Mono
Rabbit
In Vitro Diagnostic Use
7ml

Documents

Documents

PA0378

Resources

Resources

Antigen Background

Mammaglobin is a 93 kDa glycoprotein that belongs to the uteroglobin family of proteins. It was first described in 1996 and found to be overexpressed in breast cancer. Published reports suggest a role for mammaglobin in the diagnosis of metastatic breast carcinoma.
Mammaglobin has been suggested as a useful marker for carcinomas of unknown primary origin, with expression unaltered from the primary site. Additional published data suggests a role for mammaglobin in the migration and invasion of breast cancer cells.

Disclaimer

Mammaglobin is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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