Human breast cancer: immunohistochemical staining for Epithelial Membrane Antigen. Note membrane staining of neoplastic cells. Epithelial Membrane Antigen: clone GP1.4

Epithelial Membrane Antigen

epithelial-membrane-antigen

Antigen Background

Epithelial membrane antigen (EMA), also known as episialin, is reported to be expressed in a variety of normal and neoplastic epithelia. It has been reported that markers to CD45 (LCA) when used in conjunction with markers to EMA are useful in labeling cells of lymphoid origin, whereas the combination of anti-cytokeratin antibodies together with EMA is useful to characterize cells of epithelial origin. EMA is also notably described to be expressed in a subset of Hodgkin's lymphomas.

Disclaimer
Epithelial Membrane Antigen is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • This item replaces EMA-CE-SEMA-SEMA-CEEMA-R-7-CE
    EMA-L-CE
    1ml NCL-L-EMA
    GP1.4
    Liquid Concentrate
    P
  • PA0035
    7ml EMA Bond RTU Primary
    GP1.4
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

EMA-L-CE
Tumor Differentiation
GP1.4
Liquid Concentrate
No
P
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0035
Tumor Differentiation
GP1.4
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

EMA-L-CE
PA0035

Resources

Resources

Antigen Background

Epithelial membrane antigen (EMA), also known as episialin, is reported to be expressed in a variety of normal and neoplastic epithelia. It has been reported that markers to CD45 (LCA) when used in conjunction with markers to EMA are useful in labeling cells of lymphoid origin, whereas the combination of anti-cytokeratin antibodies together with EMA is useful to characterize cells of epithelial origin. EMA is also notably described to be expressed in a subset of Hodgkin's lymphomas.

Disclaimer
Epithelial Membrane Antigen is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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