Human skeletal muscle: immunohistochemical staining of HAMLET: HAMLET: clone Ham1/7B6

Dysferlin Antibodies

dysferlin-antibodies

Antigen Background

Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost. Patients with other neuromuscular conditions demonstrate normal labeling patterns.

Product Specific Information

HAMLET may require heat-induced epitope retrieval in some cases.

Disclaimer
Dysferlin Antibodies are recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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Products

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HAMLET-CE
1ml NCL-Hamlet
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HAMLET-2-CE
1ml NCL-Hamlet-2
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HAMLET-CE

HAMLET-2-CE

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