Human mantle cell lymphoma: immunohistochemical staining for CD5. Note the tumor cells show a strong membrane staining reaction. CD5: clone 4C7

CD5

cd5

Antigen Background

CD5 antigen is reported to be expressed on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed on T cells. CD5 antigen is also expressed by many T cell leukemias, lymphomas, activated T cells and on a subset of B cells located primarily in the mantle zones of normal lymph nodes. CD5 antigen expression is also reported in T cell acute lymphocytic leukemias (T-ALL), some B cell chronic lymphocytic leukemias (B-CLL) as well as B and T cell lymphomas.

Disclaimer

CD5 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD5-4C7-L-CE-H
    0.5ml NCL-L-CD5-4C7
    4C7
    Liquid Concentrate
    P (HIER)
  • CD5-4C7-L-CE
    1ml NCL-L-CD5-4C7
    4C7
    Liquid Concentrate
    P (HIER)
  • CD5-4C7-L
    1ml NCL-L-CD5-4C7
    4C7
    Liquid Concentrate
    P (HIER)
  • PA0168
    7ml CD5 Bond RTU Primary
    4C7
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD5-4C7-L-CE-H
Hematopathology
4C7
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD5-4C7-L-CE
Hematopathology
4C7
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD5-4C7-L
Hematopathology
4C7
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
Research Use Only
1ml
PA0168
Hematopathology
4C7
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

CD5-4C7-L-CE-H
CD5-4C7-L-CE
CD5-4C7-L
PA0168

Resources

Resources

Antigen Background

CD5 antigen is reported to be expressed on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed on T cells. CD5 antigen is also expressed by many T cell leukemias, lymphomas, activated T cells and on a subset of B cells located primarily in the mantle zones of normal lymph nodes. CD5 antigen expression is also reported in T cell acute lymphocytic leukemias (T-ALL), some B cell chronic lymphocytic leukemias (B-CLL) as well as B and T cell lymphomas.

Disclaimer

CD5 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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