Human mantle cell lymphoma: immunohistochemical staining for CD5. Note the tumor cells show a strong membrane staining reaction. CD5: clone 4C7

CD5

cd5

Antigen Background

CD5 antigen is reported to be expressed on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed on T cells. CD5 antigen is also expressed by many T cell leukemias, lymphomas, activated T cells and on a subset of B cells located primarily in the mantle zones of normal lymph nodes. CD5 antigen expression is also reported in T cell acute lymphocytic leukemias (T-ALL), some B cell chronic lymphocytic leukemias (B-CLL) as well as B and T cell lymphomas.

Disclaimer

CD5 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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CD5-4C7-L-CE
1ml NCL-L-CD5-4C7
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PA0168
7ml CD5 Bond RTU Primary
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CD5-4C7-L-CE

PA0168

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