Human tonsil: immunohistochemical staining of CD45 or leukocyte common antigen (LCA) in various hematolymphoid cells. CD45: clone X16/99

CD45

cd45

Antigen Background

The CD45 antigen (leukocyte common antigen) is a family of five or more high molecular weight glycoproteins present on the surface of the majority of the human leukocytes (including lymphocytes, monocytes and eosinophils) but absent from erythrocytes and platelets. Various isoforms of CD45 are generated by alternative splicing of three exons. Expression of CD45 is necessary for signaling through the T cell receptor.

Disclaimer

CD45 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • LCA-L-CE-H
    0.5ml NCL-L-LCA
    X16/99
    Liquid Concentrate
    P (HIER)
  • LCA-L-CE
    1ml NCL-L-LCA
    X16/99
    Liquid Concentrate
    P (HIER)
  • PA0042
    7ml CD45 Bond RTU Primary
    X16/99
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

LCA-L-CE-H
Hematopathology
X16/99
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
LCA-L-CE
Hematopathology
X16/99
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0042
Hematopathology
X16/99
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

LCA-L-CE-H
LCA-L-CE
PA0042

Resources

Resources

Antigen Background

The CD45 antigen (leukocyte common antigen) is a family of five or more high molecular weight glycoproteins present on the surface of the majority of the human leukocytes (including lymphocytes, monocytes and eosinophils) but absent from erythrocytes and platelets. Various isoforms of CD45 are generated by alternative splicing of three exons. Expression of CD45 is necessary for signaling through the T cell receptor.

Disclaimer

CD45 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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