Human tonsil: immunohistochemical staining for CD21 antigen. Note intense membrane staining of follicular dendritic cells. CD21: clone 2G9

CD21

cd21

Antigen Background

CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.

  • CD21-2G9-L-CE
    1ml NCL-L-CD21-2G9
    2G9
    Liquid Concentrate
    P (HIER)
  • CD21-2G9-L
    1ml NCL-L-CD21-2G9
    2G9
    Liquid Concentrate
    P (HIER)
  • PA0171
    7ml CD21 Bond RTU Primary
    2G9
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD21-2G9-L-CE
Hematopathology
2G9
Liquid Concentrate
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD21-2G9-L
Hematopathology
2G9
Liquid Concentrate
No
P (HIER)
Mono
Mouse
Research Use Only
1ml
PA0171
Hematopathology
2G9
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

CD21-2G9-L-CE
CD21-2G9-L
PA0171

Resources

Resources

Antigen Background

CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.

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