Human normal small bowel immunohsitochemisrty staining of CD103. Note membrane and cytoplasmic staining of Intraepithelial T lymphocytes. CD103: clone EP206

CD103

cd103

Antigen Background

CD103, also known as alpha E integrin & human mucosal lymphocyte antigen 1, is an integrin protein with expression on intraepithelial T cells & some peripheral regulatory T cells. CD103 is expressed at high levels on tumour-infiltrating FOXP3-positive regulatory T cells in cancer and CD103-positive T cells are strongly associated with patient survival in high-grade serous ovarian cancer.

CD103 expression has been suggested as a definitive marker of intraepithelial, tumour-specific infiltrating lymphocytes. In addition, CD103-positive cells have also been identified in a small proportion of breast cancers.

  • PA0374
    7ml CD103 (EP206) Bond RTU Primary
    EP206
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

PA0374
Hematopathology
EP206
BOND RTU
No
P (HIER)
Mono
Rabbit
In Vitro Diagnostic Use
7ml

Documents

Documents

PA0374

Resources

Resources

Antigen Background

CD103, also known as alpha E integrin & human mucosal lymphocyte antigen 1, is an integrin protein with expression on intraepithelial T cells & some peripheral regulatory T cells. CD103 is expressed at high levels on tumour-infiltrating FOXP3-positive regulatory T cells in cancer and CD103-positive T cells are strongly associated with patient survival in high-grade serous ovarian cancer.

CD103 expression has been suggested as a definitive marker of intraepithelial, tumour-specific infiltrating lymphocytes. In addition, CD103-positive cells have also been identified in a small proportion of breast cancers.

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