Human skin: immunohistochemical staining for Androgen Receptor. Note the nuclear staining of the epithelial cells. Androgen Receptor: clone AR27

Androgen Receptor

androgen-receptor

Antigen Background

Androgen receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones (androgens). The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues e.g. prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors eg osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance. Furthermore, mutation of the gene encoding androgen receptor has been reported in prostatic carcinoma.

Disclaimer

Androgen Receptor is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • AR-318-L-CE
    1ml NCL-L-AR-318
    AR27
    Liquid Concentrate
    P (HIER)

Product Specifications

Product Specifications

AR-318-L-CE
Uropathology
AR27
Liquid Concentrate
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml

Documents

Documents

AR-318-L-CE

Resources

Resources

Antigen Background

Androgen receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones (androgens). The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues e.g. prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors eg osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance. Furthermore, mutation of the gene encoding androgen receptor has been reported in prostatic carcinoma.

Disclaimer

Androgen Receptor is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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