Advancing Cancer Diagnostics, Improving Lives
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Antigen Background
c-kit proto-oncogene は、チロシンキナーゼ活性を持つ膜貫通型受容体をコードしており、血小板由来増殖因子受容体ファミリーと密接な関係があります。CD117(c-kit) は、造血、配偶子形成およびメラニン形成の過程において役割を果たしています。CD117 の発現は、消化管間質腫瘍（GIST）、小細胞性肺癌および黒色腫の研究において、特に関心が持たれています。
Disclaimer
CD117 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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