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Ki67
Informações do antígeno
O antígeno Ki67 é uma proteína nuclear, a qual é expressada em todas as partes ativas do ciclo celular (G1, S, G2 e mitose) mas está ausente em células em repouso (G0).
Em contraste com muitas outras proteínas associadas por ciclo de outras células, o antígeno Ki67 está consistentemente ausente em células quiescentes e não é detectável durante processos de reparo de DNA.
Portanto, a presença do antígeno Ki67 é estritamente associada com o ciclo celular e confinada ao núcleo, sugerindo um papel importante na manutenção e/ou regulação do clico de divisão da célula.
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