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Description de l'antigène
Le complexe CD79 est un hétérodimère à ponts disulfure associé de manière non covalente aux immunoglobulines de la membrane des lymphocytes B. Ce complexe de polypeptides et d'immunoglobulines constitue le récepteur d'antigènes des lymphocytes B. Les deux composantes de ce complexe sont appelées les CD79a et CD79b. L'antigène CD79a apparaît au stade pré-B, tôt dans la maturation, et persiste jusqu'au stade de cellule plasmatique ou il constitue un composant intracellulaire. On a détecté l'expression de l'antigène CD79a dans la majorité des leucémies aigües à type cellulaire précurseur B. Il est absent des lignées cellulaires myéloïdes et des lignées cellulaires T.
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