Antigen Background PD-1 (Programmed Death 1) is a 55KDa Type I transmembrane cell surface receptor which is expressed by T-cells during activation. It is also upregulated in B-cells, dendritic cells, natural killer cells and some myeloid cells, suggesting a broad role for PD1 in immune regulation. PD-1 interacts with at least two ligands: PD-L1 and PD-L2. PD-1/PD-L1 interaction is important in many Tcell functions including acute and chronic inflammation, cancer and immunotherapy.
Disclaimer PD-1 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
We are currently updating the product codes for a number of our Advanced Staining reagents. From January 2023 you will begin to receive products with a –U, –A or –X suffix (e.g. PAxxxx-U).
Due to manufacturing & supply chain issues, this product is currently unavailable. You may place your order and it will be fulfilled when the product is back in stock. For more help, please reach out to customer service at +1 844 534 2262 or nonurgentcs@leicabiosystems.com
Nous avons un stock limité de ce produit
Nous avons un stock limité de ce produit, mais nos produits sont continuellement en fabrication. Votre commande sera traitée, mais le délai de livraison risque dêtre un peu plus long pour cette commande.
CA
