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The TERT / 5q31 dual-color FISH probe can be used to detect deletions involving band 5q31 in MDS and RUNX1. The 5q- specific FISH probe is optimized to detect copy numbers at the CDC25C/EGR1 gene region at 5q31. The TERT (previously known as hTERT) gene region at 5p15 is included to facilitate chromosome identification.
References:
Zhao et al, 1997, PNAS, 94; 6948-6053.
Horrigan et al, 2000, Blood, 95; 2372-2377.
