The FIP1L1 / CHIC2 / PDGFRA Triple-Color FISH probe is optimized to detect the CHIC2 deletion at 4q12 associated with the FIP1L1 / PDGFRA fusion in a triple-color, split assay. It also allows the detection of translocation involving the FIP1L1 and PDGFRA region.
References: Cools et al, N Engl J Med, 2003, 348; 1201-1214. Griffin et al, 2003, PNAS, 100;7830-7835. Gotlib et al, 2004, Blood, 103;2879-2891.