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Hintergrund des Antigens
Eukaryotische Zellen enthalten eine Reihe verschiedener zytoplasmatischer filamentöser Proteine, Mikrotubuli und Mikrofilamente sowie mittelgroßer Filamente (IF).
Die Expression von Vimentin, eines Proteins von 57 kD, das zu den intermediären Filamenten gehört, wird in den meisten Zellen mesenchymalen Ursprungs einschließlich Fibroblasten, Endothelzellen, glatten Muskelzellen, Melanozyten sowie T- und B-Lymphozyten beschrieben.
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