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Hintergrund des Antigens
Myosin ist ein kontraktiles muskelspezifisches Protein, das aus zwei schweren und vier leichten Ketten besteht.
Die schwere Myosinkette besitzt zahlreiche Isoformen, spezifisch für verschiedene Muskel- oder Fasertypen, von denen einige entwicklungsreguliert sind.
Die schwere Myosinkette der glatten Muskulatur (SM-MHC) ist ein zytoplasmatisches Strukturprotein, das ein wichtiger Bestandteil des kontraktilen Apparats in glatten Muskelzellen darstellt.
Berichten zufolge ist sie für die Entwicklung glatter Muskeln spezifisch.
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