Advancing Cancer Diagnostics, Improving Lives
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Hintergrund des Antigens
Das CD34-Antigen ist ein einkettiges Glykoprotein mit einem Molekulargewicht von 110 kD.
Es wird selektiv in humanen hämatopoetischen Vorläuferzellen lymphatischen und myeloischen Ursprungs exprimiert.
Das CD34-Antigen wird außerdem im Gefäßendothel exprimiert.
Bei Klon QBEnd/10 ist eine Enzymandauung der Paraffinschnitte einer hitzeinduzierten Epitopdemaskierung vorzuziehen, da diese zu einer stärkeren Färbung und einer geringeren Hintergrundfärbung durch Elastin führt.
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