Human skin: immunohistochemical staining for Phosphorylated Akt. Akt (Phosphorylated): clone LP18

Akt (Phosphorylated)

akt-phosphorylated

Antigen Background

Akt-1, also referred to as protein kinase B (PKB) or Rac alpha is a member of the Akt serin/threonine protein kinase family. It plays an important role in many biological responses including metabolism, cell survival and growth by phosphorylation and inactivating several targets including GSK 3 beta, caspase 9, BAD and the forkhead transcription factor.

Product Specific Information

Akt-Phos is not recommended for use with PBS, since the use of PBS-based wash buffers and possibly PBS-based antibody diluents gives increased background staining and decreased staining intensity. Proprietary reagents from Leica Biosystems or TBS-based wash buffer and diluents are recommended.

Disclaimer

Akt (Phosphorylated) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • This item replaces AKT-PHOS-L-SAKT-PHOS-L-CE-SAKT-PHOS-L
    AKT-PHOS-L-CE
    1ml NCL-L-Akt-Phos
    LP18
    Liquid Concentrate
    P (HIER)

Product Specifications

Product Specifications

AKT-PHOS-L-CE
Specialized
LP18
Liquid Concentrate
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml

Documents

Documents

AKT-PHOS-L-CE

Resources

Resources

Antigen Background

Akt-1, also referred to as protein kinase B (PKB) or Rac alpha is a member of the Akt serin/threonine protein kinase family. It plays an important role in many biological responses including metabolism, cell survival and growth by phosphorylation and inactivating several targets including GSK 3 beta, caspase 9, BAD and the forkhead transcription factor.

Product Specific Information

Akt-Phos is not recommended for use with PBS, since the use of PBS-based wash buffers and possibly PBS-based antibody diluents gives increased background staining and decreased staining intensity. Proprietary reagents from Leica Biosystems or TBS-based wash buffer and diluents are recommended.

Disclaimer

Akt (Phosphorylated) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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