DLEU1 (13q14) / TP53 (17p13) hybridized to a normal metaphase (2R2G).

IVD DLEU1/TP53

ivd-dleu1-tp53
Deletion of DLEU1 (previously known as DLEU) at 13q14 indicates a rather good prognosis, deletion of TP53 (previously known as p53) at 17p13 is associated with poor prognosis. The DLEU1 (13q14) specific FISH probe is optimized to detect copy numbers at the DLEU1 gene region at 13q14. The TP53 (17p13) specific FISH probe is optimized to detect copy numbers of the TP53 gene region at 17p13.

References:
Amiel et al, 1997, Cancer Gener.Cytogenet, 97; 97-100.
Drach et al, 1998, Blood, 92; 802-809.
Stilgenbauer et al, 1998, Oncogene, 16; 1891 - 1897.
Wolf et al, 2001, Hum. Molec. Genet., 10; 1275-1285.

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KBI-10113
DLEU1 (13q14) / TP53 (17p13)
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