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Human colon: immunohistochemical staining for Cytokeratin 20. Note the intense staining of surface mucosa. Cytokeratin 20: clone Ks20.8

细胞角蛋白20

cytokeratin-20
细胞角蛋白20已被证明几乎完全局限于胃和肠上皮细胞，表皮的尿上皮细胞和默克尔细胞。细胞角蛋白20比其他I型细胞角蛋白酸性更低，由于其组织表达受限而引起人们的关注。正常组织中，细胞角蛋白20表达于肠上皮、胃凹上皮、幽门腺上部的内分泌细胞、表皮的尿路上皮和默克尔细胞。据报道，在肿瘤中，细胞角蛋白20在不同的肿瘤中表达有显著差异。表达细胞角蛋白20的肿瘤来源于正常上皮细胞，正常上皮细胞本身也表达细胞角蛋白20。结直肠癌始终表达细胞角蛋白20，而胃腺癌表达细胞角蛋白20，程度较轻的胆囊和胆管腺癌、胰腺导管细胞腺癌、粘液性卵巢肿瘤、默克尔细胞瘤和移行细胞癌也有报道表达细胞角蛋白20。

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CK20-L-H
0.5ml NCL-L-CK20

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CK20-L-CE-H
0.5ml NCL-L-CK20
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CK20-L-CE
1ml NCL-L-CK20
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CK20-L
1ml NCL-L-CK20
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CK20-561-L-CE
1ml NCL-L-CK20-561
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PA0037
30ml Cytokeratin 20 Bond RTU Primary
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PA0022
7ml Cytokeratin 20 Bond RTU Primary
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CK20-L-H
SDS IFU
CK20-L-CE-H
SDS IFU
CK20-L-CE
SDS IFU
CK20-L
SDS IFU
CK20-561-L-CE
SDS IFU
PA0037
SDS IFU
PA0022
SDS IFU

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