Human colon, gastrointestinal stromal tumor: immunohistochemical staining for CD117. Note membrane staining of neoplastic cells. CD117: clone EP10

CD117

cd117

Antigen Background

The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST), small lung cell carcinomas and in melanomas.

Disclaimer

CD117 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD117-L-CE
    Checar Disponibilidade
    1ml NCL-L-CD117
    T595
    Liquid Concentrate
    P (HIER)
  • CD117-032-L-CE
    Checar Disponibilidade
    1ml NCL-L-CD117-032
    EP10
    Liquid Concentrate
    P (HIER)
  • PA0007
    Checar Disponibilidade
    7ml CD117 (EP10) Bond RTU Primary
    EP10
    BOND RTU
    P (HIER)

Especificaç÷es de Produtos

Especificaç÷es de Produtos

CD117-L-CE
Gastrointestinal Pathology
T595
Liquid Concentrate
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD117-032-L-CE
Gastrointestinal Pathology
EP10
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0007
Gastrointestinal Pathology
EP10
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documentos

Documentos

Recursos

Recursos

Antigen Background

The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117), which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST), small lung cell carcinomas and in melanomas.

Disclaimer

CD117 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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