Advancing Cancer Diagnostics, Improving Lives
Antigen Background
Cytokeratin 8/18は、正常組織ではすべての単層腺上皮細胞に発現することが報告されています。腫瘍組織では、腺癌およびほとんどの扁平上皮癌で発現することが示されています。これらのCytokeratinは、角化型扁平上皮癌には存在しません。
Product Specific Information
Clone 5D3 reacts with human cytokeratin intermediate filament proteins of 52.5 kD and 45 kD, identified as cytokeratins 8 and 18, respectively. Clone 5D3 shares similar specificities to clone CAM5.2 (Angus B et al. Journal of Pathology. 153: 377-384 (1987)).
Cytokeratin (8/18) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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