Hybridization of SE 7 / SE 8 probe to a metaphase spread showing normal pattern (2R2G).

RUO - SE 7 / SE 8

Trisomy 8 is found as one of the genetic changes in CML, while loss of chromosome 7 is found in AML. The SE 7 (D7Z1) / SE 8 (D8Z1) FISH probes are optimized to detect repetitive sequences located in the pericentric heterochromatin of chromosome 7 and 8.

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