Human striated muscle: immunohistochemical staining for Spectrin. Note membrane staining of muscle fibers. Spectrin: clone RBC2/3D5

Spectrin

spectrin

Antigen Background

Spectrin is a cytoskeletal protein which has some structural homology with dystrophin, the protein that is defective in Duchenne and Becker muscular dystrophy. Subtle membrane damage frequently occurs during the excision and freezing of muscle biopsies. Labeling for spectrin must be used to monitor membrane integrity. NCL-SPEC1 recognizes the beta chain of spectrin in erythrocytes and muscle. NCL-SPEC1 reacts with human beta-spectrin.


Disclaimer

Spectrin is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • SPEC1-CE
    Voir Disponibilité
    1ml NCL-SPEC1
    RBC2/3D5
    Lyophilised Concentrate
    F

Caractéristiques Produits

Caractéristiques Produits

SPEC1-CE
Muscle Pathology
RBC2/3D5
Lyophilised Concentrate
No
F
Mono
Mouse
In Vitro Diagnostic Use
1ml

Documents

Documents

Ressources

Ressources

Antigen Background

Spectrin is a cytoskeletal protein which has some structural homology with dystrophin, the protein that is defective in Duchenne and Becker muscular dystrophy. Subtle membrane damage frequently occurs during the excision and freezing of muscle biopsies. Labeling for spectrin must be used to monitor membrane integrity. NCL-SPEC1 recognizes the beta chain of spectrin in erythrocytes and muscle. NCL-SPEC1 reacts with human beta-spectrin.


Disclaimer

Spectrin is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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