Advancing Cancer Diagnostics, Improving Lives
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Description de l'antigène
Le melan A, un produit du gène MART-1e, est un marqueur de différenciation des mélanocytes reconnu par les lymphocytes T cytotoxiques autologues.
D'autres marqueurs associés aux mélanomes reconnus par les lymphocytes T cytotoxiques autologues comprennent MAGE-1, MAGE-3, la tyrosinase, gp100, gp75, BAGE-1 et GAGE-1.
L'analyse de ces molécules et de leur expression dans les mélanomes individuels pourrait être utile pour l'étude de leurs rôles moléculaires dans la différenciation des mélanocytes et dans la tumorigenèse.
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