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Antigen Background
Rhabdomyosarcomas are a class of myoblast-derived soft tissue sarcomas that usually express a number of muscle-specific genes and primarily affect children and young adults. Differentiation of myogenic cells is controlled by a set of regulatory genes including MyoD1, myogenin, Myf-5 and Myf-6. Myf-4 is the human homolog of myogenin. Its gene product, together with that of Myf-3, accumulates in the nucleus of differentiated cells.
Disclaimer
Myogenin (Myf-4) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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Andorra
Australia
Austria
Belgium
Brunei Darussalam
Canada
China
Denmark
Finland
France
French Guiana
Germany
Guadeloupe
Holy See (Vatican City State)
Hong Kong
Ireland
Italy
Japan
Liechtenstein
Luxembourg
Martinique
Myanmar
Netherlands
New Caledonia
New Zealand
Norway
Philippines
Portugal
Reunion
Singapore
Spain
Sweden
Switzerland
Taiwan
Thailand
United Kingdom
Vietnam