Human large bowel: immunohistochemical staining of Neuron Specific Enolase (NSE). Note the staining in the neuronal elements and the ganglia of the longitudinal and circular smooth muscle. Neuron Specific Enolase: clone 22C9

Neuron Specific Enolase

neuron-specific-enolase

Antigen Background

Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2-phosphoglycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma ) whereas, in rats, five forms have been found. The alpha subunit and beta subunit are of approximately 47 kD and 45 kD, respectively. The gamma gamma and alpha gamma enolases are located mainly in the nervous tissue and neuroendocrine cells.

Disclaimer

Neuron Specific Enolase is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • This item replaces NSE-435-CENSE-435
    PA0435
    7ml NSE Bond RTU Primary
    22C9
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

PA0435
Neuropathology
22C9
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

PA0435

Resources

Resources

Antigen Background

Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2-phosphoglycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma ) whereas, in rats, five forms have been found. The alpha subunit and beta subunit are of approximately 47 kD and 45 kD, respectively. The gamma gamma and alpha gamma enolases are located mainly in the nervous tissue and neuroendocrine cells.

Disclaimer

Neuron Specific Enolase is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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