Human tonsil: immunohistochemical staining with Kappa Light Chain: clone CH15

Kappa Light Chain

kappa-light-chain

Antigen Background

Immunoglobulins are polypeptides and comprise five major classes; immunoglobulin G (IgG), IgA, IgM, IgD and IgE. Each immunoglobulin consists of two identical heavy (H) chains and two identical light (L) chains.These are also subdivided into sub classes eg IgG1. There are two classes of light chain; kappa and lambda. The ratio of kappa chains and light chains varies between Ig classes and sub classes, but is also species specific. In humans, approximately 60 percent of light chains are kappa. However, in any particular immunoglobulin molecule the light chain will be either kappa or lambda. B cells contain either kappa or lambda mRNA.

Disclaimer

Kappa Light Chain is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • KAP-581-L-CE
    1ml NCL-L-KAP-581
    CH15
    Liquid Concentrate
    P (ENZYME)
  • PA0606
    7ml Kappa Light Chain Bond RTU Primary
    CH15
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

KAP-581-L-CE
Hematopathology
CH15
Liquid Concentrate
Yes
P (ENZYME)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0606
Hematopathology
CH15
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

KAP-581-L-CE
PA0606

Resources

Resources

Antigen Background

Immunoglobulins are polypeptides and comprise five major classes; immunoglobulin G (IgG), IgA, IgM, IgD and IgE. Each immunoglobulin consists of two identical heavy (H) chains and two identical light (L) chains.These are also subdivided into sub classes eg IgG1. There are two classes of light chain; kappa and lambda. The ratio of kappa chains and light chains varies between Ig classes and sub classes, but is also species specific. In humans, approximately 60 percent of light chains are kappa. However, in any particular immunoglobulin molecule the light chain will be either kappa or lambda. B cells contain either kappa or lambda mRNA.

Disclaimer

Kappa Light Chain is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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