Human tonsil: immunohistochemical staining for cytokeratin, Multi. Note the cytokeratins demonstrated in stratified squamous epithelium. The negative cells in the epithelium are infiltrating lymphocytes. Cytokeratin, Multi (4/5/6/8/10/13/18): clone C-11

Cytokeratin, Multi (4/5/6/8/10/13/18)

cytokeratin-multi-4568101318

Antigen Background

Cytokeratins 4, 5, 6, 8, 10, 13 and 18 are differentially expressed between a variety of normal, reactive and neoplastic epithelia and also simple epithelium and both basal and suprabasal layers of cornifying and noncornifying squamous epithelium.

Cytokeratin, Multi (4/5/6/8/10/13/18) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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Antigen Background

Cytokeratins 4, 5, 6, 8, 10, 13 and 18 are differentially expressed between a variety of normal, reactive and neoplastic epithelia and also simple epithelium and both basal and suprabasal layers of cornifying and noncornifying squamous epithelium.

Cytokeratin, Multi (4/5/6/8/10/13/18) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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