Human colonic adenocarcinoma: immunohistochemical staining for Cytokeratin 18. Note: cytoplasmic staining of malignant epithelial cells. Cytokeratin 18: clone DC-10

Cytokeratin 18

cytokeratin-18

Antigen Background

Cytokeratin 18 is normally co-expressed with cytokeratin 8 and is found in most simple ductal and glandular epithelia.

Product Specific Information

CK18 reacts with the acidic cytokeratin intermediate filament protein (45 kD) identified as cytokeratin 18. Cytokeratin 18 is reported not to be expressed in stratified squamous epithelium on most squamous cell carcinomas.

Disclaimer

Cytokeratin 18 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

Product Specifications

Product Specifications

Documents

Documents

Resources

Resources

Antigen Background

Cytokeratin 18 is normally co-expressed with cytokeratin 8 and is found in most simple ductal and glandular epithelia.

Product Specific Information

CK18 reacts with the acidic cytokeratin intermediate filament protein (45 kD) identified as cytokeratin 18. Cytokeratin 18 is reported not to be expressed in stratified squamous epithelium on most squamous cell carcinomas.

Disclaimer

Cytokeratin 18 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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