Human lymph node, T cell lymphoma: immunohistochemical staining for CD8. Note the neoplastic cells show a moderate to strong, distinct membrane staining reaction. CD8: clone 4B11

CD8

cd8

Antigen Background

The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35% of human peripheral blood lymphocytes.The CD8 antigen is reported to be detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15-30% of bone marrow cells.

Disclaimer

CD8 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD8-4B11-L-H
    0.5ml NCL-L-CD8-4B11
    4B11
    Liquid Concentrate
    P (HIER)
  • CD8-4B11-L-CE-H
    0.5ml NCL-L-CD8-4B11
    4B11
    Liquid Concentrate
    P (HIER)
  • CD8-4B11-L
    1ml NCL-L-CD8-4B11
    4B11
    Liquid Concentrate
    P (HIER)
  • CD8-4B11-L-CE
    1ml NCL-L-CD8-4B11
    4B11
    Liquid Concentrate
    P (HIER)
  • PA0183
    7ml CD8 Bond RTU Primary
    4B11
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD8-4B11-L-H
Hematopathology
4B11
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
Research Use Only
1ml
CD8-4B11-L-CE-H
Hematopathology
4B11
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD8-4B11-L
Hematopathology
4B11
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
Research Use Only
1ml
CD8-4B11-L-CE
Hematopathology
4B11
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0183
Hematopathology
4B11
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

CD8-4B11-L-H
CD8-4B11-L-CE-H
CD8-4B11-L
CD8-4B11-L-CE
PA0183

Resources

Resources

Antigen Background

The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35% of human peripheral blood lymphocytes.The CD8 antigen is reported to be detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15-30% of bone marrow cells.

Disclaimer

CD8 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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