T cell lymphoma: immunohistochemical staining for CD7. Note the intense membrane staining of tumor cells. CD7: clone LP15

CD7

cd7

Antigen Background

The CD7 molecule is a membrane-bound glycoprotein of 40 kD and is the earliest T cell specific antigen to be expressed in lymphocytes. CD7 antigen is also the only early marker to persist throughout differentiation. The function and role of the CD7 molecule has not yet been fully identified, although the activation of T cells with gamma/delta receptors has been proposed based on mAb-induced activation. CD7 antigen is reported to be found on the majority of peripheral blood T cells, most natural killer cells and thymocytes.

Disclaimer

CD7 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD7-580-L-CE
    1ml NCL-L-CD7-580
    LP15
    Liquid Concentrate
    P (HIER)
  • PA0266
    7ml CD7 Bond RTU Primary
    LP15
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD7-580-L-CE
Hematopathology
LP15
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0266
Hematopathology
LP15
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

CD7-580-L-CE
PA0266

Resources

Resources

Antigen Background

The CD7 molecule is a membrane-bound glycoprotein of 40 kD and is the earliest T cell specific antigen to be expressed in lymphocytes. CD7 antigen is also the only early marker to persist throughout differentiation. The function and role of the CD7 molecule has not yet been fully identified, although the activation of T cells with gamma/delta receptors has been proposed based on mAb-induced activation. CD7 antigen is reported to be found on the majority of peripheral blood T cells, most natural killer cells and thymocytes.

Disclaimer

CD7 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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